85-1774-55　bpV(HOpic) 5mg　CAS No:722494-26-0　044614

特徴

• bpV(OHpic) is a bisperoxovanadium inhibitor of protein phosphotyrosine phosphatases with selectivity for PTEN, phosphatase and tensin homolog, a tumor suppressor phosphatase involved in cell cycle regulation. IC50 values for bpV(HOpic) are 14 nM for PTEN compared to 4.9 μM for PTPβ and 25.3 μM for PTP-1β. bpV(HOpic) has been shown to enhance PI3K/Akt signaling that could prevent myocardium from ischemia-reperfusion injury.
• Synonyms:Dipotassium bisperoxo (5-hydroxypyridine-2-carboxyl) oxovanadate (V).
• Molecular Formula:K2[VO(O2)2C6H4NO3]
• Molecular Weight:347.24
• Form:Supplied as a yellow crystalline powder.
• Purity:≥95% (51V-NMR)
• Solubility:Soluble in DMSO and water
• Note: Not stable in water. Decomposition starts immediately after solubilization. Rate of decomposition is slower in dry DMSO.
• Storage and Stability:Short Term Storage: +4°CLong Term Storage: -20°CMay be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Moisture and light sensitive.