85-1773-99　Annexin V, Recombinant, Human (ATTO 647N) (Annexin A5, Endonexin II, Lipocortin V, Placental Anticoagulant Protein I, Calphobindin I, Vascular Anticoagulant-alpha) 100Tests　044560

特徴

• Annexin V is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Annexin V competes for phosphatidylserine binding sites (e.g. platelets) with prothrombin or coagulation factors and inhibis the activity of phospholipase A1. Antibodies directed against annexin V are found in patients with a disease called the antiphospholipid syndrome(APS), a thrombophilic disease associated with autoantibodies against phospholipid compounds. Annexin V is used as a probe in the "annexin V affinity assay" to detect cells that have expressed phosphatidylserine on the cell surface, a feature found in apoptosis and other forms of cell death.
• Sequence:Recombinant human annexin V fused to a GST-tag.
• Storage and Stability:Short-term Storage: +4°CLong-term Storage: +4°CStable for at least 1 year after receipt when stored at +4°C.

仕様

• Size：100Tests
• Source Antigen：Recombinant, Human, E. coli
• Grade：Highly Purified
• Purity：>95% (SDS-PAGE)
• Form：In PBS, pH 7.4, 0.02% sodium azide.
• Specificity：Binds to phosphatidylserine (PS).
• Molecular Weight Non Ab：52
• EU Commodity Code：30021019
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