85-1772-45　Chromomycin A3 5mg　CAS No:7059-24-7　C5180

特徴

• Chromomycin A3 is the major component of the chromomycin complex of the aureolic acid class, isolated from several Streptomyces species and first reported in 1960. Chromomycin A3 exhibits a broad biological profile as an antibacterial, antifungal and antitumor agent. It binds reversibly to GC-specific DNA ligand in the minor groove which inhibits transcription, DNA gyrase and topoisomerase II. The intense UV spectrum and strong fluorescence makes chromomycin a useful stain for DNA.
• Synonyms:(1S)-1-C-[(2S,3S)-7-[[4-O-Acetyl-2,6-dideoxy-3-O-(2,6-dideoxy-4-O-methyl-α-D-lyxo-hexopyranosyl)-β-D-lyxo-hexopyranosyl]oxy]-3-[[O-4-O-acetyl-2,6-dideoxy-3-C-methyl-α-L-arabino-hexopyranosyl-(1→3)-O-2,6-dideoxy-β-D-arabino-hexopyranosyl-(1→3)-2,6-dideoxy-β-D-arabino-hexopyranosyl]oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-5-deoxy-1-O-methyl-D-threo-2-pentulose; Aburamycin B; Antibiotic B 599; CMA3; NSC 58514; Toyomycin; 3D-O-(4-O-Acetyl-2,6-dideoxy-3-C-methyl-α-L-arabino-hexopyranosyl)-7-methyl-olivomycin D
• Molecular Formula:C₅₇H₈₂O₂₆
• Molecular Weight:1183.25
• Appearance:Yellow powder
• Purity:≥98% (HPLC)
• Melting Point:xxx°C
• Solubility:xxx
• Storage and Stability:May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Source:Chromomycin A3 from Stretomyces griseus.
• Molecular Weight:~1183.3
• Solubility:Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
• Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.