Bestatin is "pseudo"-dipeptide isolated from Streptomyces olivreticuli in 1976. Bestatin is potent aminopeptidase B inhibitor with no carboxypeptidase activity. Bestatin acts as an immunomodulator by activation of macrophages and T-lymphocytes. Bestatin also exhibits good antitumor activity and is under clinical investigation.
Source:Bestatin from Streptomyces sp.
Molecular Weight:~308.4
Solubility:Soluble in ethanol, methanol, DMF or DMSO. Moderate water solubility.
Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
