85-1772-22　UBE2D3, Recombinant, Human, aa1-149, His-Tag (Ubiquitin-conjugating Enzyme E2 D3, Ubiquitin-protein Ligase D3, Ubiquitin carrier protein D3, Ubiquitin-conjugating Enzyme E2-17kD 3, Ubiquitin-conjugating Enzyme E2(17)KB 3, UBCH5C) 250ug　U0880-08D

特徴

• UBE2D3, the modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.
• Source:Recombinant corresponding to aa1-149 from human UBE2D3, fused to His-tag at N-terminal expressed in E.coli.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MLSNRKCLSK ELSDLARDPP AQCSAGPVGD DMFHWQATIM GPNDSPYQGG VFFLTIHFPT DYPFKPPKVA FTTRIYHPNI NSNGSICLDI LRSQWSPALT ISKVLLSICS LLCDPNPDDP LVPEIARIYK TDRDKYNRIS REWTQKYAM
• Molecular Weight:~19.1kD (MALDI-TOF)
• Enzyme Activity:Not determined. This product is recommended for use in applications that do not require a catalytically active form of the protein.
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.