85-1770-55　HDDC3, Recombinant, Human, aa1-140 His-Tag (Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1, HD Domain-containing Protein 3, Metazoan SpoT Homolog 1, MESH1, Penta-phosphate Guanosine-3'-pyrophosphohydrolase, (ppGpp)ase, MESH1) 100ug　029660

特徴

• HDDC3, contains an active site for ppGpp hydrolysis and a conserved His-Asp-box motif for Mn(2+) binding. Consistent with these structural data, HDDC3 efficiently catalyzes hydrolysis of guanosine 3',5'-diphosphate (ppGpp) both in vitro and in vivo. HDDC3 also suppresses SpoT-deficient lethality and RelA-induced delayed cell growth in bacteria.
• Source:Recombinant corresponding to aa1-140 from human HDDC3, fused to His-tag at N-terminal expressed in E.coli.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MGSEAAQLLE AADFAARKHR QQRRKDPEGT PYINHPIGVA RILTHEAGIT DIVVLQAALL HDTVEDTDTT LDEVELHFGA QVRRLVEEVT DDKTLPKLER KRLQVEQAPH SSPGAKLVKL ADKLYNLRDL NRCTPEVKIQ
• Molecular Weight:~17.9kD (MALDI-TOF)
• Enzyme Activity:Not determined. This product is recommended for use in applications that do not require a catalytically active form of the protein.
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.