85-1769-85　CFL2, Recombinant, Human, aa1-166, His-Tag (Cofilin-2, Cofilin, Muscle Isoform) 500ug　C7506-52

特徴

• CFL2 belongs to the actin-binding proteins ADF family that contains 1 ADF-H domain. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. Defects in CFL2 are the cause of nemaline myopathy type 7 (NEM7).
• Source:Recombinant corresponding to aa1-166 from human CFL2, fused to His-tag at N-terminal expressed in E.coli.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASGVTVNDE VIKVFNDMKV RKSSTQEEIK KRKKAVLFCL SDDKRQIIVE EAKQILVGDI GDTVEDPYTS FVKLLPLNDC RYALYDATYE TKESKKEDLV FIFWAPESAP LKSKMIYASS KDAIKKKFTG IKHEWQVNGL DDIKDRSTLG EKLGGNVVVS LEGKPL
• Molecular Weight:~20.9kD (MALDI-TOF)
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

仕様

• Size：500ug
• Source Antigen：Recombinant, E.coli
• Grade：Highly Purified
• Purity：~90% (SDS-PAGE)
• Form：Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 2mM DTT, 10% glycerol, 50mM sodium chloride.
• Molecular Weight Non Ab：20.9
• EU Commodity Code：30021019
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