A lignan isolated from the bark of Fagara plants and from sesame oil. Studies show that it has has multiple functions such as cholesterol-lowering and anti-hypertensive activities. It induces the expression of the gene for aldehyde dehydrogenase, an alcohol-metabolizing enzyme suggesting it regulates the metabolism of lipids, xenobiotics, and alcohol at the mRNA level.
Melting Point:121-123°C
Solubility:Chloroform, DMSO
Method for Determining Identity:Proton NMR (DMSO-d6 and CDCl3) and MS
TLC Conditions:SiO2; Hexane : Ethyl Acetate (2:1). Visualized with UV and AMCS (single spot; Rf= 0.4).
Specific Rotation:+66.5°
Storage and Stability:Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
