85-1699-22　Physostigmine 250mg　CAS No:57-47-6　019677

特徴

• A parasympathomimetic, specifically, a reversible cholinesterase inhibitor obtained from the Calabar bean, used to treat glaucoma and delayed gastric emptying. Physostigmine is an alkaloid and noted to act as a potent and reversible inhibitor of cholinesterase. Physostigmine is also reported to form a slowly degrading carbamylated enzyme complex with AChE (acetylcholinesterase). This compound has been used as a positive control in a study investigating acetylcholinesterase inhibitors for potential antihelminthic drug targets.
• Synonyms:(3aS-cis)-1,2,3,3a,8,8a-Hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indol-5-ol Methylcarbamate Ester; Eserine; Synapton; Cogmine; Eserine; Esromiotin; MCV 4484; NIH 10421; NSC 30782; (3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl methylcarbamate
• Molecular Formula:C₁₅H₂₁N₃O₂
• Molecular Weight:275.35
• Appearance:White to pale orange solid
• Purity:≥99%
• Melting Point:102-106°C
• Solubility:Chloroform (Slightly, Sonicated), DMSO (Slightly), Ethanol (Slightly), Methanol
• Storage and Stability:Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.