85-1684-42　［取扱停止］4-(Methylnitrosamino)-1-(3-pyridyl-d4)-1-butanone (NNK-d4) 1mg　017226

特徴

• Labeled NNK. This compound was present in the highest concentrations in smokeless tobacco out of the nitrosamines identified. It is likely to be important in the etiology of cancers of the lung, oral cavity, and pancreas in people who use tabacco products. Readily produces cancer in rats and hamsters. Carcinogen.
• Synonyms:4-(N-Methyl-N-nitrosamino)-1-(3-pyridyl-d4)-1-butanone; NNK-d4
• Molecular Formula:C₁₀H₉D₄N₃O₂
• Molecular Weight:211.25
• Purity (HPLC, Isotopic):≥95%
• Appearance:Off-white to light brown solid
• Melting Point:As reported
• Solubility:Chloroform (Slightly), Methanol (Slightly)
• Method for Determining Identity:Proton NMR Spectroscopic and Mass Spectrometric Analysis
• TLC Conditions:SiO2; Dichloromethane: Methanol = 9: 1; Visualized with UV and AMCS; Single Spot, Rf = 0.25
• Elemental Analysis:Calculated: %C: 56.85, %H: 6.21 %N: 19.89
• Normalized Intensity:As reported
• Storage and Stability:Store at -20°C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap.