A Cyclophosphamide analog which induces apoptosis dose and time dependently in lymphoblastoid cells, with clearly more apoptosis in p53wt cells. Antitumor agent.
Synonyms:rel-2-[[(2R,4R)-2-[Bis(2-chloroethyl)amino]tetrahydro-2-oxido-2H-1,3,2-oxazaphosphorin-4-yl]thio]ethanesulfonic Acid Sodium; Mafosfamid Sodium; Z 7557; cis-Mafosfamide Sodium
Molecular Formula:C9H18Cl2N2NaO5PS2
Molecular Weight:423.25
Purity:≥95%
Appearance:White to pale beige solid
Melting Point:>85°C (dec.) (lit)
Solubility:DMSO (slightly), Methanol (slightly)
Method for Determining Identity:Proton NMR and Mass Spectrometric Analysis
Storage and Stability:May be stored at RT for short-term only. Long-term storage is recommended at -20°C for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Very Hygroscopic. Store under inert atmosphere.
