85-1649-83　Eflornithine Hydrochloride Monoydrate 500mg　CAS No:96020-91-6,Free amine: 70052-12-9　011044

特徴

• Irreversible inhibitor of ornithine decarboxylase, an enzyme involved in polyamine biosynthesis. Antineoplastic; antipneumocystic; antiprotozoal (Trypanosoma). Used in the treatment of hirsutism.
• Synonyms:2-(Difluoromethyl)-DL-ornithine Hydrochloride Hydrate; 2-(Difluoromethyl)ornithine; DFMO; DL-2-(Difluoromethyl)ornithine; DL-α-(Difluoromethyl)ornithine; Elfornithine; MDL 71782; MDL 71782A; Ornidyl; RFI 71782; RMI 71782; α,δ-Diamino-α-(difluoromethyl)valeric Acid; α-(Difluoromethyl)-DL-ornithine; α-(Difluoromethyl)ornithine
• Molecular Formula:C₆H₁₅ClF₂N₂O₃
• Molecular Weight:236.64
• Purity:≥98%
• Appearance:White to off-white solid
• Melting Point:>210°C (dec.)
• Solubility:Water (Slightly)
• Method for Determining Identity:Proton NMR Spectroscopic, 19F NMR and Mass Spectrometric Analysis
• TLC Conditions:C18: Methanol: Acetic Acid = 6:2:1 Visualized with Ninhydrin Single spot, RF=0.75
• Elmental Analysis:Calculated: %C: 30.45, %H: 6.39, %N: 11.84
• Chloride:As reported
• Storage and Stability:Powder is stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original bottle after thawing and prior to removing the cap.