85-1600-92　Auranofin 25mg　CAS No:34031-32-8　002985

特徴

• Auranofin is a new oral gold-based antiarthritis drug. Auranofin inhibits various leukocyte activation pathways at multiple sites. Auranofin inhibits the release of inflammatory mediators from human macrophages, basophils, and pulmonary mast cells. Auranofin is an efficient inducer of mitochondrial membrane permeability transition pore in the presence of calcium ions related to its inhibition of mitochondrial thioredoxin reductase.
• Synonyms:(S)-Triphenylphosphine gold(I) 2,3,4,6-tetra-O-acetyl-b-D-thioglucopyranoside; 1-Thio-b-D-glucopyranosatotriethylphosphine gold-2,3,4,6-tetraacetate; 3,4,5-Triacetyloxy-6-(acetyloxymethyl) oxane-2-thiolate triethylphosphanium
• Molecular Formula:C₂₀H₃₄AuO₉PS
• Molecular Weight:678.48
• Appearance:White to off-white crystalline powder
• Assay (Gold content):28-31%
• Specific Optical Rotation[α]20 (c=1, CHCl):-40 to -58°
• Melting Point:110-118°C
• Solubility:Chloroform (Slightly), Methanol (Slightly)
• Storage and Stability:May be stored at RT for short-term only. Long-term storage is recommended at -20°C. Stable for 6 months ater receipt.