85-1593-79　Alamethicin (Antibiotic U-22324) 1mg　CAS No:27061-78-5　001726

特徴

• Alamethicin is a peptide antibiotic, produced by the fungus Trichoderma viride. Alamethicin contains the non-proteinogenic amino acid 2-aminoisobutyric acid (Aib), which strongly induces helical peptide structures. In cell membranes, it forms voltage-dependent ion channels by aggregation of four to six molecules.
• Synonyms:(3S,12R)-1-((S)-1-((6S,12S,15S,21S,30S)-1-((R)-1-(2-Acetamido-2- methylpropanoyl)pyrrolidin-2-yl)-15-(3-amino-3-oxopropyl)-30-isobutyl-21-isopropyl- 3,3,6,9,9,2,18,18,24,24,33,33-dodecamethyl-1,4,7,10,13,16,19,22,25,28,31- undecaoxo-2,5,8,11,14,17,20,23,26,29,32-undecaazatetratriacontan-34- oyl)pyrrolidin-2-yl)-12-(((R)-5-amino-1-(((S)-1-hydroxy-3-phenylpropan-2-yl)amino)-1, 5-dioxopentan-2-yl)carbamoyl)-3-isopropyl-6,6,9,9-tetramethyl-1,4,7,10-tetraoxo-2,5, 8,11-tetraazapentadecan-15-oic Acid
• Molecular Formula:C₉₂H₁₅₀N₂₂O₂₅
• Molecular Weight:1964.31
• Form:Supplied as an off-white to brown crystalline.
• Purity:≥90%
• Melting Point:>172°C (dec.)
• Solubility:DMSO (Slightly ,Heated), Methanol (Slightly)
• Storage and Stability:May be stored at -20°C. Stable for 6 months after receipt at -20°C.
• Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
• Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.