85-1593-61　S-(5'-Adenosyl)-L-Methionine-d3 Disulfate Salt (Mixture of Diastereomers) 1mg　001674

特徴

• Labelled S-(5’-Adenosyl)-L-methionine. Methyl donor; cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. It is also involved in regulating liver function, growth, and response to injury.
• Synonyms:5’-[[(3S)-3-Amino-3-carboxypropyl](methyl-d3)sulfonio]-5’-deoxyadenosine Disulfate; 5’-[(L-3-Amino-3-carboxypropyl)(methyl-d3)sulfonio]-5’-deoxyadenosine Disulfate; S-Adenosylmethionine-d3 Disulfate; Active Methionine-d3 Disulfate; Ademetionine-d3 Disulfate; L-S-Adenosylmethionin-d3 Disulfate; S-Adenosyl-L-methionine-d3 Disulfate
• Molecular Formula:C₁₅H₂₃D₃N₆O₁₃S₃
• Molecular Weight:597.61
• Purity:≥95% Chemical, ≥98% Isotopic
• Appearance:White to pale yellow solid
• Melting Point:>102°C (dec.)
• Solubility:Water (Slightly)
• Method for Determining Identity:Proton NMR spectroscopic analysis and Mass spectrometric analysis
• TLC Conditions:C18; Methanol: Water: Acetic Acid=5:5:0.02; Visualized with UV and KMnO4; Rf=0.40
• Elemental Analysis:Calculated: %C: 30.15, %H: 4.39, %N: 14.06
• Normalized Intensity:As Reported
• Sulfate Content (Ion Chromatography):~33%
• Water Content (Elemental Analysis):~3%
• Storage and Stability:Store at -20°C under an atmosphere of inert gas. Stable for 6 months after receipt. Caution: Hygroscopic.