Small nuclear ribonucleoprotein polypeptide G, also known as SNRPG, belongs to the snRNP Sm proteins family. There are at least seven isoforms, B/B, E, F, G, D1, D2, and D3. This class of common proteins plays an essential role in the biogenesis of the snRNPs. The genes encoding human Sm G map to chromosomes 2. In addition, these proteins represent the major targets for the so-called anti-Sm auto-antibodies which are diagnostic for systemic lupus erythematosus (SLE). One class of these autoantibodies reacts specifically with native Sm E-F-G complexes.
Source:Recombinant corresponding to aa1-76 from human SNRPG, fused to His-tag at N-terminus expressed in E.coli.
AA Sequence:MGSSHHHHHH SSGLVPRGSH MSKAHPPELK KFMDKKLSLK LNGGRHVQGI LRGFDPFMNLVIDECVEMAT SGQQNNIGMV VIRGNSIIML EALERV
Molecular Weight:~10.6kD (96aa), confirmed by MALDI-TOF
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size：50ug
Source Antigen：Recombinant, E. coli
Grade：Highly Purified
Purity：~95% (SDS-PAGE)
Form：Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 1mM DTT, 0.1M sodium chloride, 50% glycerol.
