GSKIP (GSK3 B interaction protein) is defined as a naturally occurring protein that is homologous with the GSK3beta interaction domain of Axin and is able to negatively regulate GSK3beta of the Wnt signaling pathway. GSKIP may affect GSK3B activity on neurite outgrowth by inhibiting the specific phosphorylation of tau (ser396).
Source:Recombinant corresponding to aa1-139 from human GSKIP, fused to His-tag at N-terminus expressed in E.coli.
Molecular Weight:~17.8kD (159aa), confirmed by MALDI-TOF
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size：100ug
Source Antigen：Recombinant, E. coli
Grade：Highly Purified
Purity：~95% (SDS-PAGE)
Form：Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0), 1mM DTT, 50mM sodium chloride,10% glycerol.
