CSTA, also known as Stefin A, is thiol protease inhibitors that form complexes with papain and the cathepsins B, H and L. The protein is one of the precursor proteins of the cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. CSTA is thought to be a tumor suppressor, since an inverse correlation seems to exist between the level of CSTA and tumor progression, in several malignancies.
Source:Recombinant corresponding to aa1-98 from human CSTA, fused to His-tag at N-terminus expressed in E.coli.
Molecular Weight:~13.1kD (118aa), confirmed by MALDI-TOF
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size:100ug
Source Antigen:Recombinant, E.coli
Grade:Highly Purified
Purity:~95% (SDS-PAGE)
Form:Supplied as a liquid in 20mM Tris-HCl buffer, pH 8, 1mM DTT, 10% glycerol.