BST2, also known as bone marrow stromal antigen 2, is involved in the growth and development of B-cells. BST2 is a human cellular protein which inhibits retrovirus infection by preventing the diffusion of virus particles after budding from infected cells. Initially discovered as an inhibitor to HIV-1 infection in the absence of Vpu, tetherin has also been shown to inhibit the release of other viruses such as the Lassa and Marburg virions. Also, this protein may play a role in B-cell activation in rheumatoid arthritis. Purified by using conventional chromatography.
Source:Recombinant corresponding to aa50-161 of human BST2, fused to His-tag at N-terminal, expressed in E.coli.
Molecular Weight:~14.8kD (133aa), confirmed by MALDI-TOF
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size：50ug
Source Antigen：Recombinant, E.coli
Grade：Purified
Purity：~80% (SDS-PAGE)
Form：Supplied as a liquid in 20mM Tris-HCl buffer, pH8, 0.1Msodium chloride, 1mM DTT, 20% glycerol.
