PAI-1 protein has a single substitution at either the P12 or P14 position on the reactive center loop facilitating a conversion of the proteins to a substrate for proteases rather than an inhibitor. Useful for mechanistic studies.
Source:PAI-1 from human plasma
Solubility:2~5mg/ml
Absorption: 280nm
Molecular Weight: 43kD
Activity:Substitution at the P14 position on the reactive center loop creates a PAI-1 substrate for proteinases rather than an inhibitor.
Storage and Stability:Aliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:500ug
Source Antigen:Recombinant from human plasma
Grade:Highly Purified
Purity:~98% (SDS-PAGE)
Form:Supplied as a liquid in 0.5M sodium phosphate, 0.15M sodium chloride, pH 6.6.