The monohydrochloride salt is the form used to prepare formulations of this drug for clinical use. Note that the solubility properties of the mono- and di-HCl salts are different. Kinase inhibitor; has antivasospastic properties.
Solubility:Very soluble in water, up to 200mg/ml or more; soluble in DMSO up to about 10mg/ml; not soluble in ethanol; addition of an aqueous solution of this dihydrochloride salt into a buffer solution may significantly alter its solubility.
Storage and Stability:May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.