85-1562-08　Doramapimod, Free Base (1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]urea) (BIRB 796, DB03044, D03736) 5mg　CAS No:285983-48-4　D9023

特徴

• Doramapimod is a protein kinase inhibitor with a >330-fold selectivity for p38 MAPK compared with 12 other protein kinases. In contrast to other p38 MAPK inhibitors (e.g., SB203580), doramapimod prevents both the kinetic activity and phosphorylation of p38 MAPK by binding to the ATP pocket as well as to a novel allosteric binding site on p38 MAPK.
• Solubility:Soluble in DMSO at 50mg/ml. Soluble in ethanol at 33mg/ml. Very poorly soluble in water. Maximum solubility in plain water is estimated to be about 5-20uM.
• Melting Point:114-142ºC
• Elemental Anaylsis:C = 70.56%H = 7.07%N = 13.27%
• Storage and Stability:May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

仕様

• Size：5mg
• Grade：Highly Purified
• Purity：~90%
• Form：Supplied as a white to off-white powder.
• Molecular Formula：C31H37N5O3
• Molecular Weight Non Ab：527.66
• EU Commodity Code：38220090
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• 製品の仕様は予告なく変更になる場合がございます。最新仕様はメーカーホームページをご確認ください。
• CAS No ：285983-48-4

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