85-1561-97　Capecitabine (5’-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine, Ro-9-1978, Xeloda) 500mg　CAS No:154361-50-9　C1077-05B

特徴

• Capecitabine is a pre-prodrug of 5-fluorouracil (5-FU). After oral uptake, capecitabine is first metabolized to 5'-deoxy-5-fluorocytidine (5'-DFCR), which happens mainly in the liver by carboxyl-esterase. The metabolite is converted to 5'-deoxy-5-fluoro-uridine (5'-DFUR) by cytidine deaminase in liver and tumor tissue. Then 5'-DFUR is converted to 5-FU intracellularly by thymidine phosphorylase, which is often expressed in tumor tissue.
• Solubility:Soluble in DMSO at 100mg/ml; soluble in ethanol at 12.5mg/ml with slight warming; soluble in water at 2mg/ml with slight warming; buffers, serum, or other additives may increase or decrease the aqueous solubility.
• Storage and Stability:May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

仕様

• Size：500mg
• Grade：Highly Purified
• Purity：~99%
• Form：Supplied as a white to off-white powder.
• Molecular Formula：C15H22FN3O6
• Molecular Weight Non Ab：359.35
• EU Commodity Code：38220090
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• CAS No ：154361-50-9

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