85-1561-81　A-769662 (6,7-Dihydro-4-hydroxy-3-(2'-hydroxy[1,1'-biphenyl]-4-yl)-6-oxo-thieno[2,3-b]pyridine-5-carbonitrile) 10mg　CAS No:844499-71-4　A0001-68U

特徴

• A-769662 is a potent, reversible activator of AMP-activated protein kinase (AMPK). AMPK is an alpha beta gamma heterotrimer and plays an important role in regulating cellular and whole-body metabolism. A-769662 only activates AMPK heterotrimers containing the B1 subunit. A-769662 activates AMPK through the beta subunit carbohydrate-binding module and the gamma subunit but not the AMP-binding sites.
• Solubility: Soluble in DMSO at 33mg/ml; soluble in ethanol at 5mg/ml with slight warming; very poorly soluble in water; maximum solubility in plain water is estimated to be about 50-100uM; buffers, serum, or other additives may increase or decrease the aqueous solubility.
• Melting Point:277-280ºC
• Elemental Analysis:CalculatedC: 64.25%H: 3.64%N: 7.49%S: 8.58%
• Storage and Stability:May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

仕様

• Size：10mg
• Grade：Highly Purified
• Purity：~99%
• Form：Supplied as an off-white powder.
• Molecular Formula：C20H12N2O3S
• Molecular Weight Non Ab：360.39
• EU Commodity Code：38220090
• この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
• 製品の仕様は予告なく変更になる場合がございます。最新仕様はメーカーホームページをご確認ください。
• CAS No ：844499-71-4

• 【試薬に関するお問合せ】
• アズワン株式会社 試薬・プロセス材料グループ
• TEL：06-6447-8641
• FAX：06-6447-8642
• E-mail：[email protected]