Reticulocalbin 1(RCN1) is a calcium-binding protein. It binds calcium and may regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. High conservation ofaa residues outside of these motifs, in comparison to mouse reticulocalbin, is consistent with a possible biochemical function besides that of calcium binding. In human endothelial and prostate cancer cell lines this protein localizes to the plasma membrane.
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size：50ug
Source Antigen：Recombinant corresponding to human RCN1 fused to His-tag at N-terminus, expressed in E. coli (NP_002892).
Grade：Purified
Purity：~80% (SDS-PAGE). Purified by using conventional chromatography techniques
Form：Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 100mM sodium chloride, 1mM DTT, 10% glycerol
