Beta2-microglobulin (B2MG) is a small molecule of 11,199dalton (99 amino acids). Its structure and amino acid sequence are identical to the small unit of major histocompatibility complex and similar to the CH3 region of IgG (1, 2). Elevated serum concentrations suggest increased B2MG production. The phenomenon is seen in patients with autoimmune diseases (5,6), viral infections (4) and cancers involving white blood cells, such as lymphoma and multiple myeloma (3). B2MG content exists in minute amount in urine. Increased B2MG in urine suggests nephrotubulointerstitial disorder or urinary tract infection (7).
Storage and Stability:Store other components at 4°C. Stable for at least 6 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap.