Human cardiac troponin I is the inhibitory subunit of troponin involved in confering calcium sensitivity to muscle actomyosin ATPase activity. Mutation of the TNN13 gene can lead to familial hypotrophic cardiomyopathy 7 (CMH7), a hereditary heart condition characterized by asymetric ventricular hypertrophy (Kimura et al. 1997). Other cardiomyopathies also occur as a result of mutations in the TNN13 gene.
Source:Troponin I, Cardiac from Human heart.
Applications:Suitable for use in ELISA. Other applications not tested.
Recommended Dilutions:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size：10ug
Source Antigen：Human heart
Grade：Highly Purified
Purity：≥95% (SDS PAGE).
Form：Supplied as a liquid in 20mM Tris, 7M Urea, 5mM EDTA, 15mM mercaptoethanol.
