Brain and acute leukemia, cytoplasmic (BAALC) is localizes to both the membrane and the cytoplasm and exists as multiple alternatively spliced isoforms. Expressed by hematopoetic and neural cells, BAALC interacts with CaMKII-alpha and is thought to play a role in synaptic function at postsynaptic lipid rafts. Overexpression of BAALC concomitant predict adverse clinical outcome and may define important risk factor in cytogenetically normal acute myeloid leukemia (AML). Recombinant human BAALC, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Source:Recombinant corresponding to human BAALC, his-tagged, expressed in E. coli.
Storage and Stability:Aliquot to avoid repeated freezing and thawing and freeze at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 6 months.
仕様
Size：100ug
Source Antigen：Recombinant, E.coli
Grade：Affinity Purified
Purity：~95% (SDS-PAGE) Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in 20mM Tris-HCl, pH8.0, 1mM DTT, 20% glycerol, 2mM EDTA.
