CA19-9 (Sialyl Lewis a) is a carbohydrate antigenic determinant identified as a sialylated lacto-N-fucopentose II, an oligosaccharide biochemically related to the Lewis a blood group antigen. In malignant tissues positive staining of tumor cells is observed in most adenocarcinomas of the pancreas and stomach, and in a large proportion of colon and gall bladder tumors. The antigen is also expressed in approximately half of primary and metastatic ovarian tumors. In normal tissues, positive staining is also observed in column or epithelium of the pancreas stomach, liver, gall bladder and in bronchial glands of the lung.
Source: Human metastatic liver carcinoma
Activity:~330KU/ml (Roche Elecsys)
Applications:Suitable for use as Immunogen, calibrator in immunoassays and in vitro studies. Other applications not tested.
Recommended Dilutions:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size：250KU
Source Antigen：Human metastatic liver carcinoma
Grade：Purified
Purity：Purified by gel filtration and column chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 3% sucrose, 0.05% sodium azide.
