Doxorubicin is the most extensively studied of a family of highly fluorescent anthracycline antibiotics produced by several Streptomyces species, first reported in 1967 and later approved for human therapeutic use as an antitumor agent for the treatment of a wide range of cancers. Doxorubicin has also been reported to exhibit anti-HIV and antibacterial activity. The mode of action of doxorubicin is thought to be due to intercalation of DNA and inhibition of nucleic acid synthesis.
Molecular Weight:543.5
Source:Streptomyces peucetius MST-AS5775
Purity:≥99% (HPLC)
Apperance:Supplied as an orange red solid
Solubility:Soluble in ethanol, methanol, DMF and DMSO. Poor water solubility.
Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Light Sensitive.
