85-1545-65　Fibroblast Growth Factor 12, Recombinant, Human (FGF12, Fibroblast Growth Factor Homologous Factor 1, FHF1, Myocyte Activating Factor, FGF12B) 100ug　F4212-15B

特徴

• FGF12 (Fibroblast growth factor 12) is a member of the FGF superfamily of molecules which currently stands at 22 members. The FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. FGF12 binds to IB2 (islet brain-2), a cellular kinase scaffold, and voltage gated sodium channels and also plays an important role in intracellular signaling and ion exchange.
• Recombinant human FGF12 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
• Source:Recombinant corresponding to aa1-181 of human FGF12 (His-tagged) expressed in E.coli.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MESKEPQLKG IVTRLFSQQG YFLQMHPDGT IDGTKDENSD YTLFNLIPVG LRVVAIQGVK ASLYVAMNGE GYLYSSDVFT PECKFKESVF ENYYVIYSST LYRQQESGRA WFLGLNKEGQ IMKGNRVKKT KPSSHFVPKPIEVCMYREQS LHEIGEKQGR SRKSSGTPTM NGGKVVNQDS T
• Biological Activity: Not determined
• Applications:Suitable for use in Western Blot. Other applications not tested.
• Recommended Dilution:Western Blot: 3ug/ml 15% SDS-PAGE, Optimal dilutions to be determined by the researcher.
• Storage and Stability:Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.