IPP-1, 1-171aa, Human, His-tagged, Recombinant, E. coli
Full name: Protein phosphatase inhibitor-1
NCBI Accession: NP_006732
Synonyms: IPP-1, I-1, PPI-1
Protein phosphatase inhibitor-1 (IPP-1) plays an important role in the regulation of glycogen metabolism through inhibition of type-1 protein serine/threonine phosphatase(PP1) activity, and it has been implicated in the regulation of cell growth. IPP-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. In the presence of calcium, PPI-1 is inactivated by calcineurin (or PP2B).
Recombinant human IPP-1, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Storage and Stability:May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size：50ug
Source Antigen：Recombinant, E. coli
Grade：Highly Purified
Purity：≥ 90% by SDS PAGE
Form：Supplied as a liquid in 50mM Tris, pH 8.0, 0.1mM PMSF, 1mM EDTA, 1mM DTT, 10% glycerol.
