IL-1 beta is an inflammatory cytokine that might modulate angiogenesis by directly interacting with vascular endothelial cells or enhancing the production of proangiogenic factors via paracrine control. IL-1 beta stimulates endothelial cell migration and proliferation, adhesion-molecule expression, inflammatory mediator production, and leukocyte recruitment. IL-1 beta is required for tumor growth, metastasis, and angiogenesis in several animal models.
Recombinant protein corresponding to aa118-269 with a His-Tag from mouse Interleukin 1 beta, expressed in E. coli. Purified by using conventional chroma- tography techniques.
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size：100ug
Source Antigen：E. coli
Grade：Highly Purified
Purity：≥90% by SDS PAGE
Form：Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 10% glycerol.
