ANPB (natriuretic peptide receptor B) is one of two integral membrane receptors for natriuretic peptides. Both ANPA and ANPB contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain), an helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. ANPB is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity.
Synthetic peptide (QNRLLIRAREDFGVE) corresponding to aa288-302 of human NPR-B
Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with 0.1% acetic acid. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size：1mg
Source Antigen：Synthetic
Grade：Highly Purified
Purity：≥95% (HPLC)
Form：Supplied as a lyophilized powder. No preservatives added. Reconstitute with 0.1% acetic acid.
