The tetronic acid, chlorothricin is an unusual macrocyclic antibiotic from a Streptomyces sp.. It shows inhibitory activity against cholesterol biosynthesis from mevalonate and inhibits pyruvate carboxylases purified from rat liver, chicken liver and Azotobacter vinelandii.
Solubility: Soluble in ethyl acetate, ethanol, methanol, DMF or DMSO.
Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with ethyl acetate, ethanol, methanol, DMF or DMSO..Aliquot and store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
