A metabolite of Tamoxifen, a nonsteroidal estrogen antagonist of interest in the treatment of some forms of breast cancer. Tamoxifen is a Protein Kinase C inhibitor, and induces apoptosis in human malignant glioma cell lines
Melting Point:141-413°C
Solubility:Methanol
Method for Determining Identity:Proton NMR Spectroscopic Analysis
TLC Conditions:SiO2; Dichloromethane: Methanol: NH4OH; 60:10:1; Visualized with UV and AMCS; Single spot; Rf=0.35
Storage and Stability:May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Hygroscopic.