85-1527-85　Securinine (Securinan-11-one) 5mg　CAS No:5610-40-2　S0380

特徴

• Extracted from leaves and roots of Securinega suffruticosa Rehder. The most widely studied of these alkaloids, Securinine, is a specific GABA receptor antagonist and has been found to have significant in vivo CNS activity.
• Synonyms:(6S,11aR,11bS)-9,10,11,11a-Tetrahydro-8H-6,11b-methanofuro[2,3-c]pyrido[1,2-a]azepin-2(6H)-one; 1,2,3,4,10,10a-Hexahydro-10-hydroxy-6,10-methanopyrido [1,2-a]azepine-9(6H),α-acetic Acid γ-Lactone; Securinan-11-one; (-)-Securinine; NSC 107413; Securinin; l-Securinine
• Molecular Formula:C₁₃H₁₅NO₂
• Molecular Weight:217.26
• Form:Supplied as a pale yellow to yellow solid
• Melting Point:140-144°C
• Solubility:Chloroform (slightly), Ethanol (slightly)
• Method for Determining Identity:Proton NMR (CD3OD) and Mass Spectrometric Analysis
• TLC Conditions:SiO2; Dichloromethane: Methanol= 9:1; Visualized with UV KMnO4; Single Spot, Rf=0.35.
• Elemental Analysis:Calculated: %C:71.87, %H:6.96, %N:6.45
• Specific Rotation (c=0.50, Ethanol):-1066.6°
• Storage and Stability:May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
• Toxicity and Hazards:All products should be handled by qualified personnel only, trained in laboratory procedures.