85-1518-82　［受注停止］Nicotianamine 1mg　CAS No:34441-14-0　N2561-80

特徴

• Phytosiderophores are produced in higher plants as iron chelating amino acids that promote uptake of iron from soil. Nicotianamine is a metal chelator and phytosiderophore precursor produced in plants that has a role in the uptake, translocation, and intracellular transport of metals.1 Treating lettuce (L. sativa) with a Cu(OH)2-based pesticide raises nicotianamine levels 12- to 27-fold compared to non-pesticide treated plants.2 Nicotianamine also inhibits rabbit angiotensin-coverting enzyme (ACE) (IC50 = 0.26 μM) and human recombinant ACE2 (IC50 = 84 nM).3,4
• Synonyms:(αS,2S)-α-[[(3S)-3-Amino-3-carboxypropyl]amino]-2-carboxy-1-azetidinebutanoic Acid; [2S-[1[αR*(R*)],2R*]]-α-[(3-Amino-3-carboxypropyl)amino]-2-carboxy- 1-azetidinebutanoic Acid
• Molecular Formula:C12H21N3O6
• Molecular Weight:303.31
• Purity:~90%
• Appearance:White to off-white solid
• Solubility:Methanol (Slightly), Water (Slightly)
• Melting Point:>200°C (dec.)
• Method for Determining Identity:Proton NMR (D2O) Spectroscopic and Mass Spectrometric Analysis
• TLC Conditions:C18; Methanol: Water = 6:4; Visualized with KMnO4; Single spot, Rf=0.50
• Specific Rotation:-37.6º (c=1, Water)
• Water Content (Karl Fischer):~10%
• Atmosphere:Inert Gas
• Storage and Stability:May be stored at RT for short-term only. Long-term storage is recommended at -20°C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Store under inert atmosphere.