2-Methoxy 17β-Estradiol is a natural metabolite of 17β-Estradiol which is devoid of estrogenic activity. Inhibits cell proliferation and angiogenesis. 2-Methoxy 17β-Estradiol binds to the colchicine binding site of tubulin, and has been suggested to function as a natural regulator of microtubule assembly and function.
Source:Synthetic
Purity:~90%
Form:Supplied as a off white solid.
Molecular Formula:C₁₉H₂₆O₃
Melting Point:181-184°C
Solubility:Chloroform, Dichloromethane
Method for Determining Identity:Proton NMR Spectroscopic Analysis
TLC Conditions:SiO2; Hexane: Ethyl Acetate; 3:2; Visualized with UV and AMCS; Single spot; Rf=0.4.
Storage and Stability:May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
