85-1509-99　L-Methionine [R,S]-Sulfoximine 500mg　CAS No:15985-39-4　M3022-05

特徴

• Methionine sulfoximine inhibits both glutamine synthetase and g-glutamylcysteine synthetase. Working concentrations for inhibition of g-glutamylcysteine synthetase are 0.2-2.0mM (52% inhibition occured at 100mM).Methionine sulfoximine is also a toxic byproduct of nitrogen trichloride, a compound that was used to bleach unprocessed wheat flour prior to 1968. The compound has been investigated as a potential neurotoxin linked to diseases such as amyotrophic lateral sclerosis (ALS) and Parkinson’s disease.
• Synonyms:L-S-[3-Amino-3-carboxypropyl]-S-methyl-[R,S]-sulfoximine; (2S)-2-Amino-4-(S-methylsulfonimidoyl)butanoic Acid
• Molecular Formula:C₅H₁₂N₂O₃S
• Molecular Weight:180.23
• Appearance:White to off-white solid
• Purity:≥98%
• Melting Point:>210°C (dec.)
• Solubility:Formic Acid, Water
• Storage and Stability:Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.