85-1509-22　Menaquinone 4 (Vitamin K2 (20), MK 4) 50mg　CAS No:863-61-6　M2876

特徴

• Menaquinone 4 (MK-4) is the predominant homolog of vitamin K2 and is composed of a naphthoquinone base with four isoprenoid units in the side chain.1 It is formed primarily via conversion of vitamin K1 (Item No. 21051) in vivo and accumulates in various tissues, including the brain.2,3 MK-4 halts the cell cycle at the G phase in HepG2, Hep3B, and Huh7 hepatocellular carcinoma cells in a concentration-dependent manner.4 It also inhibits I?B kinase (IKK) activity, I?Ba phosphorylation, and the transcriptional activity of NF-?B. Vitamin K2 may have a role in bone metabolism.1
• Synonyms:(E,E,E)-2-Methyl-3-(3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenyl)-1,4-naphthalenedione; Menatetrenone; Vitamin K2(20); Kaytwo; MK 4
• Molecular Weight:444.7
• Molecular Formula:C31H40O2
• Appearance:White to off-white to yellow solid
• Purity:≥98%
• Storage and Stability:Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Melting Point: 35°C
• Storage and Stability:May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.