85-1502-51　［取扱停止］o-Hydroxy Atorvastatin Lactone 10mg　CAS No:163217-74-1　H9036-50

特徴

• A metabolite of Atorvastin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
• Synonyms:5-(4-Fluorophenyl)-N-(2-hydroxyphenyl)-2-(1-methylethyl)-4-phenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide; Atorvastatin 2-Hydroxy Lactone
• Molecular Formula:C₃₃H₃₃FN₂O₅
• Molecular Weight:556.62
• Appearance:Off-white to pale yellow solid
• Purity:~90%
• Melting Point:96-102°C
• Method for Determining Identity:Proton NMR (CD3OD) Spectroscopic and Mass Spectrometric Analysis
• TLC Conditions:SiO2; Dichloromethane: Methanol=9:1; Visualized with UV and AMCS; Rf=0.60.
• Ethyl Acetate:As Reported
• Solubility:Chloroform (Slightly), Methanol (Slightly)
• Storage and Stability:May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.