85-1499-83　5-Fluorouracil (5-FU), USP 250g　CAS No:51-21-8　F5275-45

特徴

• A potent antineoplastic agent in clinical use. Also an inhibitor of DNA synthesis. 5-Fluoro Uracil is is an DNA/RNA synthesis inhibitor. It is used as a potent antitumor agent since it interrupts nucleotide synthetic by inhibiting thymidylate synthase.
• Synonyms:5-Fluoro-2,4(1H,3H)pyrimidinedione; 2,4-Dihydroxy-5-fluoropyrimidine; 5-FU; 5-Fluoropyrimidine-2,4-diol; Adrucil; Arumel; Carac; Fluoroplex; Fluorouracil; Flurablastin; Queroplex; Ro 2-9757; Timazin; U 8953; Ulup; Flucytosine EP Impurity A; 5-FU
• Molecular Formula:C₄H₃FN₂O₂
• Molecular Weight:130.08
• Purity:98-102% (HPLC)
• Appearance:White crystalline powder
• Melting Point:262-265°C (dec.) (lit)
• Heavy Metals:≤0.002%
• Infrared Spectrum:Conforms to reference
• Loss on Drying:≤0.5%
• Residue on Ignition:≤0.1%
• Fluorine:13.9-15%
• Identity:To 5ml of solution (1:100), add 1ml of bromide water TS. The bromide color is discharged.
• Storage and Stability:May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Warning:Highly toxic!