85-1498-59　Etoposide 500mg　CAS No:33419-42-0　E8800-01

特徴

• An antitumor agent. A topoisomerase II inhibitor. A derivative of podophyllotoxin that has major activity against a number of tumors, including germ cell neoplasms, small cell lung cancer, and malignant lymphoma. Induces apoptosis in human T cells, mouse thymocytes, and HL-60 human leukemia cells.
• Synonyms:4′-Demethylepipodophyllotoxin; 9-(4,6-O-ethylidene-β-D-glucopyranoside); (5R,5aR,8aR,9S)-9-[[4,6-O-(1R)-Ethylidene-β-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)furo[3’,4’:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one; EPEG; VP 16-213; VePesid; Vepesid J; Zuyeyidal; trans-Etoposide
• Molecular Formula:C₂₉H₃₂O₁₃
• Molecular Weight:588.56
• Melting Point:253-255°C
• Solubility:Chloroform (Slightly), Methanol (Slightly)
• Method for Determining Identity:Proton H NMR (CD3OD) Mass Spectroscopic analysis
• TLC Conditions:SiO2; Dichloromethane; Methanol; 9:1; Visualized with UV and AMCS; Single spot; Rf=0.5.
• Specific Rotion:-104.3º (c-0.6, Chloroform)
• Storage and Stability:May be stored at RT for short-term only. Long-term storage is recommended at -20°C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
• Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.