85-1486-06　Cyanoethyl N,N-Diisopropyl Phosphoamidochloridite (2-Cyanoethyl n,n-Diisopropylchlorophosphoramidite) 1g　C8406-10

特徴

• 2-Cyanoethyl diisopropylchlorophosphoramidite is a useful intermediate in organic synthesis. It acts as a protecting reagent in DNA synthesis. It is involved in the selective monophosphorylation of carbohydrates and nucleosides. It plays an essential role in the conversion of protected ribonucleosides to phosphoramidites. It is also utilized as phosphitylating reagent for 3'-hydroxyl groups in the synthesis of oligodeoxyribonucleotides.
• Synonyms:2-Cyanoethyl n,n-Diisopropylchlorophosphoramidite; Chloro(diisopropylamino)-β-cyanoethoxyphosphine
• Molecular Formula:C₉H₁₈ClN₂OP
• Molecular Weight:236.68
• Appearance:Hazy, colorless to yellow oil.
• Purity:≥95%
• Proton NMR Spectroscopic Analysis:Conforms to reference
• Boiling Point:103-105°/0.08mm
• Flash Point:>110°(230°F)
• Refractive Index:1.4780
• Density:1.061g/mL at 25°C (lit.)
• Solubility:Benzene, Dichloromethane (Slightly), Chloroform
• Stability:Hydrolyzes, Very unstable
• Storage and Stability:May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Hygroscopic, Store under Inert atmosphere. Reacts violently with water. Incompatible with alcohols and strong bases.