85-1481-28　Celecoxib (Celebrex, 4-[5-(4-Methylphenyl)-3-trifluoromethyl)-1H-pyrazol-yl]benzenesulfonamide) 500mg　CAS No:169590-42-5　C2600

特徴

• Celecoxib is a highly selective COX-2 inhibitor and primarily inhibits prostaglandin production. Celecoxib is approximately 7.6-fold more selective for COX-2 inhibition over COX-1. This specificity allows celecoxib to reduce inflammation and pain while minimizing gastrointestinal adverse drug reactions (e.g. stomach ulcers) that are common with non-selective non-steroidal anti-inflammatory drugs (NSAIDs).
• Synonyms:Celecoxib, 4-[5-(4-Methylphenyl)-3-trifluoromethyl)-1H-pyrazol-yl]benzenesulfonamide
• Molecular Formula:C17H14F3N3O2S
• Molecular Weight:381.37
• Appearance:White solid
• Purity:≥99%
• Melting Point:157-159°C
• Solubility:DMSO, Dichloromethane, Ether, Ethyl Acetate, Methanol
• Soluble in DMSO at 200mg/ml; soluble in ethanol at 100mg/ml; very poorly soluble in water; maximum solubility in plain water is estimated to be about 10-50uM; buffers, serum, or other additives may increase or decrease the aqueous solubility.
• Storage and Stability:Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Pfizer Compound