Analog of Cisplatin with reduced nephrotoxicity. Carboplatin is a platinum-based antineoplastic drug that damages DNA by forming intrastrand cross-links with neighboring guanine residues. Tumors acquire resistance to these drugs through the loss of DNA-mismatch repair (MMR) activity and the resultant decrease in the induction of programmed cell death.
Appearance:White crystalline powder
Purity:≥98%
Loss on Drying:≤0.5%
Melting Point:228-230˚C
Solubility:Water
Storage and Stability:May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
