An unsaturated omega-6 fatty acid constituent of the phospholipids of cell membranes. Precursor to a large family of eicosanoids.1,2 Acts as a second messenger independent of metabolism.3-6 Retrograde messenger in long-term potentiation in the nervous system.7 Inhibits Ras-GAP.8
Atmosphere:Inert gas
Solubility:Sparingly soluble in chlororform
Method for Determining Identity:Proton NMR (CDCl3) and MS
TLC Conditions:SiO2; Hexane : Ethyl Acetate (8 : 2). Visualized with AMCS and KMnO4 (Rf =0.50).
Storage and Stability:Store in amber vial under inert atmosphere at -86°C. Product subject to oxidation. Protect from air. Caution: Light and temperature sensitive. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.