The active metabolite of Leflunomide, a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis. LEF-M interferes with dendritic cell function.
Source:Synthetic
Purity:~90%
Form:Supplied as a white solid
Solubility:DMSO (Heated)
Melting Point:220-223ºC
Method for Determining Identity:Proton NMR and Mass Spectroscopic Analysis
TLC Conditions:SiO2: Ethyl Acetate: Hexane: Acetic acid; 7ml: 3ml: 5 drops; Visualized with UV and AMCS; Single spot; Rf=0.35.
Storage and Stability:May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.