Human CD95 (APO-1/FAS) is a type I cell surface glycoprotein that is strongly upregulated on activated T cells, B cells, NK cells and thymocytes (1). CD95 plays an important role in programmed cell death or apoptosis (2). Apoptosis appears to be a mechanism for regulating the immune response (3, 4). CD95-huIg fusion protein blocks binding of anti-human CD95 antibody to cells expressing CD95.
Functional Application: CD95-huIg fusion protein inhibits CD95 ligand mediated apoptosis of Jurkat cells.
Human CD95 (APO-1/FAS)huIg/Biotin Fusion Protein*
Molecular Structure: A soluble fusion protein consisting of the extracellular (175aa) domain of human CD95 fused to human IgG1 Fc (234aa).
Transfectant Cell Line: CHO
Applications:Suitable for use in ELISA. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer
仕様
Size：25ug
Source Antigen：CHO cells
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in FBS, 50mM Sodium Phosphate pH 7.5, 100mM Potassium Chloride, 150mM NaCl, 0.5mg/ml Gentamicin Sulfate.
